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RC271.A-C
Chemotherapy and Targeted Therapy, Brain and Cognitive Issues, Dental and Teeth, Eyes, Complementary and Integrative Medicine, Mucositis, Esophageal, Oral, Gastrointestinal, Drugs,

RC271 - Cancer Therapy Issues
Mucositis Oral, Esophageal, Eye and Gastrointestinal Problems and Solutions


RC271.A62 - Complementary and Integrative Medicine
RC271.C5 - Chemotherapy And Other Oncology Drug Issues


Cancer Therapy Issues - Mucositis Oral, Esophageal, Eye and Gastrointestinal Problems and Solutions
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RC271.E390.1 - Smile: Protect Your Mouth
Rosemary Elliott-Snow, RDH
It is very important that the oncology and dental teams work together to maintain optimal health before, during and following therapy. Preexisting or undetected oral disease may cause more complication in your overall health.
http://www.cancersupportivecare.com/dental.html
Link added 2006-05-21; reviewed 2008-09-27
RC271.R68.1 - Introduction to Mucositis - Oral, Esophageal and Gastrointestinal Problems and Solutions
Ernest H Rosenbaum, MD, Sol Silverman, MA, DDS, Bernadette Festa, MS, RD, Isadora R. Rosenbaum, MA, Julie Matel, MS, RD, Rosemary Elliott-Snow, RDH, and Robert J. Ignoffo, PharmD
http://www.cancersupportivecare.com/mucositis.html
Link added 2006-02-02; reviewed 2008-09-27
RC271.R68.2 - Mucositis: Chemotherapy Problems and Solutions
Ernest H Rosenbaum, MD, Sol Silverman, MA, DDS, Bernadette Festa, MS, RD, Isadora R. Rosenbaum, M.A., Julie Matel, MS, RD, Rosemary Elliott-Snow, RDH, and Robert J. Ignoffo, Pharm D
Cancer therapy or cancer itself may cause changes in your body chemistry that result in a loss of appetite. Pain, nausea, vomiting, diarrhea or a sore or dry mouth may make eating difficult and cause loss of interest in food. Ideally, the physician, nurse or a registered dietitian should be working with the oncologist and yourself.
http://www.cancersupportivecare.com/drug.php
Link added 2006-05-21; reviewed 2008-09-27
RC271.R68.3 - Mucositis: Esophageal and Gastrointestinal Problems and Solutions
Ernest H Rosenbaum, MD, Sol Silverman, MA, DDS, Bernadette Festa, MS, RD, Isadora R. Rosenbaum, M.A., Julie Matel, MS, RD, Rosemary Elliott-Snow, RDH, and Robert J. Ignoffo, Pharm D
A normal high-protein, high-calorie diet with supplements as needed will help your sore mouth or tongue heal faster. Drinking lots of fluids will also help with healing as well as making your mouth sores more comfortable
http://www.cancersupportivecare.com/gastro.php
Link added 2006-02-02; reviewed 2008-09-27
RC271.R68.4 - Mucositis: Oral Problems and Solutions
Ernest H Rosenbaum, MD, Sol Silverman, MA, DDS, Bernadette Festa, MS, RD, Isadora R. Rosenbaum, MA, Julie Matel, MS, RD, Rosemary Elliott-Snow, RDH, and Robert J. Ignoffo, PharmD
Adequate nutrition can be challenging for patients with cancer. Physical problems may interfere with food intake and proper nutrition. Patients with mouth or throat pain can interfere with chewing and compound difficulties in swallowing. Tooth and gum disease further complicate the problem. A resultant weight loss tends to weakness, inactivity, discouragement, further anorexia, and susceptibility to infection.
http://www.cancersupportivecare.com/oral.php
Link added 2006-02-02; reviewed 2008-09-27
RC271.R68.5 - Mucositis and Targeted Therapies
Ernest H Rosenbaum, MD
New patient toxicities occur when targeted therapies usually monoclonal antibodies or small molecules such as tyrosine kinase inhibitors are given in conjunction with more traditional chemotherapy drugs. Mucosal injury can be a combination of either or both with mouth ulcers and diarrhea prominent.
http://www.cancersupportivecare.com/target.html
Link added 2008-09-27;
RC271.R68.6 - Vision and Hearing Comorbidities
Ernest H Rosenbaum, MD
Eye and Hearing problems from chemotherapy, radiation, hormonal, and bisphosphonate therapy may include; damaged inner ear sound perception, vertigo, dizziness, cataracts, blurry vision, impaired night vision, light sensitivity, dry or watery eyes and pain. Get your eyes and hearing checked.
http://www.cancersupportivecare.com/Survivorship/eareye.html
Link added 2009-11-08;
RC271.R68.7 - Vision and Hearing Comorbidities
Ernest H Rosenbaum, MD
Eye and Hearing problems from chemotherapy, radiation, hormonal, and bisphosphonate therapy may include; damaged inner ear sound perception, vertigo, dizziness, cataracts, blurry vision, impaired night vision, light sensitivity, dry or watery eyes and pain. Get your eyes and hearing checked.
http://www.cancerlynx.com/eareye.html
Link added 2009-11-08;
RC271.R68.8 - Dental Health and Cancer Survivors
Ernest H Rosenbaum, MD
Dental health during and after cancer therapy is important. Common infections of the teeth and gums may become dangerous health hazards. Radiation, high-dose chemotherapy, bone marrow transplant and medications affect parts of the body not directly associated with the specific disease. Treatment may cause ulcerations, pain and injury to the mouth.
http://www.cancersupportivecare.com/Survivorship/mouth.html
Link added 2009-11-07;
RC271.S354.1 - Handout Mucositis: Problems and Solutions - page 1
Julie Schwenka, PharmD, Ernest H. Rosenbaum, MD, Alexandra Andrews, Charles M. Dollbaum, MD, PhD and Robert J. Ignoffo, PharmD
It is important to know who is at risk of mucositis and to prevent complications to help improve quality of life and maximize your therapy. These risk factors include radiation to the head and neck, high dose chemotherapy, bone marrow transplantation, certain single agent anti-cancer drugs or a combination of these. Symptoms of mucositis should be treated as soon as they appear. It is important to be educated about proper nutrition and oral hygiene to help prevent or lessen these symptoms. Once you are aware of proper nutrition, you will be able to maintain adequate hydration, maintain your immunity and help prevent nausea as well as protecting your teeth
http://www.cancersupportivecare.com/mucositispage1.pdf
Link added 2006-05-21; reviewed 2008-09-27
RC271.S354.2 - Handout Mucositis: Problems and Solutions - page 2
Julie Schwenka, PharmD, Ernest H. Rosenbaum, MD, Alexandra Andrews, Charles M. Dollbaum, MD, PhD and Robert J. Ignoffo, PharmD
It is important to know who is at risk of mucositis and to prevent complications to help improve quality of life and maximize your therapy. These risk factors include radiation to the head and neck, high dose chemotherapy, bone marrow transplantation, certain single agent anti-cancer drugs or a combination of these. Symptoms of mucositis should be treated as soon as they appear. It is important to be educated about proper nutrition and oral hygiene to help prevent or lessen these symptoms. Once you are aware of proper nutrition, you will be able to maintain adequate hydration, maintain your immunity and help prevent nausea as well as protecting your teeth
http://www.cancersupportivecare.com/mucositispage2.pdf
Link added 2006-05-21; reviewed 2008-09-27
RC271.S354.3 - Handout Mucositis: Problems and Solutions
Julie Schwenka, PharmD, Ernest H. Rosenbaum, MD, Alexandra Andrews, Charles M. Dollbaum, MD, PhD and Robert J. Ignoffo, PharmD
It is important to know who is at risk of mucositis and to prevent complications to help improve quality of life and maximize your therapy. These risk factors include radiation to the head and neck, high dose chemotherapy, bone marrow transplantation, certain single agent anti-cancer drugs or a combination of these. Symptoms of mucositis should be treated as soon as they appear. It is important to be educated about proper nutrition and oral hygiene to help prevent or lessen these symptoms. Once you are aware of proper nutrition, you will be able to maintain adequate hydration, maintain your immunity and help prevent nausea as well as protecting your teeth
http://www.cancersupportivecare.com/mucositishandout.php
Link added 2006-05-21; reviewed 2008-09-27

Complementary and Integrative Medicine
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RC271.A62.B412.1 - Complementary Medications and Chemotherapy
Sharya Vaughn Bourdet, PharmD, Robert Ignoffo, PharmD, Clinical Professor UCSF
The use of complementary and alternative medicine for the prevention and treatment of various diseases has become more popular in recent years than ever before.Several types of alternative therapies exist, including herbals, vitamins, and dietary products
http://www.cancersupportivecare.com/complementary.html
Link added 2006-05-21; reviewed 2008-09-27
RC271.A62.B247.1 - Making Healthy Decisions about Complementary Medicine
William M. Buchholz, MD
Consumers must learn to evaluate health information critically to make sure they get value for what they pay. Good decisions require understanding what is needed, how likely the treatment is to provide it, and a means to verify that the treatment is working.
http://www.cancerlynx.com/camdecisions.html
Link added 2006-05-05; reviewed 2008-09-27
RC271.A62.F13.1 - Complementary/Alternative Therapies from a patient perspective
Ann Fonfa
Ann Fonfa, founder of The Annie Appleseed Project and a breast cancer survivor, has testified in Congress and to the Food & Drug Administration about a patientr's need for CAM information
http://www.annieappleseedproject.org
Link added 2009-01-02;
RC271.A62.F25.2 - Integrative Herbal Medicine
Bernadette Festa, MS, RD
RC271.A62.F25.1 - Integrative Medicine - Herbal Medicines
Bernadette Festa, MS, RD
Currently not a lot of solid research has been done on herbs. There are some preparations being studied for minimizing side effects of treatment, however the current thinking is to minimize or avoid most herbs during treatment.
http://www.cancersupportivecare.com/herbalmedicine.html
Link added 2006-05-21; reviewed 2008-09-27
RC271.A62.F25.2 - Integrative Herbal Medicine
Bernadette Festa, MS, RD
Currently not a lot of solid research has been done on herbs. There are some preparations being studied for minimizing side effects of treatment, however the current thinking is to minimize or avoid most herbs during treatment, due to the possibility of herbs interfering with treatment.
http://www.cancerlynx.com/integrative.html
Link added 2006-05-21; reviewed 2008-09-27
RC271.A62.F25.3 - Heathly Sample Menu
Bernadette Festa, MS, RD
Including more antioxidant foods in the diet is important and concentrating on the food itself rather than the supplements is a given. Here is a sample menu incorporating the knowledge that we have today

http://www.cancerlynx.com/samplemenu.html
Link added 2008-11-21;
RC271.A62.J33.1 - East Meets West: Integrating Complementary Medicine into Your Care
RC271.A62.J33.1 - East Meets West: Integrating Complementary Medicine into Your Care
Bradly Jacobs, MD, MPH
Integrative Medicine is based four primary principles: Emphasizing respect for the human capacity for healing, Placing importance on the relationship between the practitioner and the patient, Creating a collaborative team-based approach.
http://www.cancersupportivecare.com/eastwest.html
Link added 2006-05-21; reviewed 2008-09-27
R271.A62.J33.2 - East Meets West: Integrating Complementary Medicine into Your Care
Bradly Jacobs, MD, MPH
Integrative Medicine is based four primary principles: Emphasizing respect for the human capacity for healing, Placing importance on the relationship between the practitioner and the patient, Creating a collaborative team-based approach to patient care among practitioners, and Encouraging patients to participate in their care and to learn about selfcare methods in order to promote their own wellness.
http://www.cancerlynx.com/eastwest.html
Link added 2006-05-21; reviewed 2008-09-27
RC271.A62.N303.1 - Complementary Medications and Chemotherapy
Zoe-lina Ngo, PharmD
Scientific data on benefits of alternative medicine are few, therefore, the use of alternative medicine is generally not recommended. However, scientific data suggests that the use of complementary medicine may be safe and effective
http://www.cancersupportivecare.com/herbal.html
Link added 2006-05-14; reviewed 2008-09-27

Chemotherapy And Oncology Drug Issues
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RC271.C5.C48.1 Doxil Side Effects Relief Information Sheet
Christina Carr and Susan Temple, RN, MSN
Doxil Information Sheet for the Prophylaxis and/or treatment of ppe and stomatitis includes practical tips for dealing with side effects
http://www.cancerlynx.com/doxil.html
Link added 2006-05-21; reviewed 2008-09-27
RC271.C5.F181.1 - Chemotherapy and Vision
Paul T. Finger, MD, FACS
Chemotherapy is most commonly used for non ocular metastatic tumors and for various forms of eye cancer. Chemotherapeutic agents for eye cancers are typically employed for retinoblastoma and conjunctival tumors
http://www.cancerlynx.com/eyechemo.html
Link added 2006-05-21; reviewed 2008-09-27
RC271.C5.F377.1 - Mental (Cognitive) Changes in Survivors
Patricia Fobair, LMSW, MPH
Survivors should know that mental impairment called chemo-brain could happen. There is little doubt that even subtle cognitive problems can be a real complication of hormone manipulations, chemotherapy, radiation and biologic response modifiers.
http://www.cancersupportivecare.com/Survivor/cognitive.html Link added 2008-09-27;
RC271.C5.I387.1 - Preventing Chemotherapy Toxicities And Other Issues On Drugs Used In Oncology
Dr. Robert Ignoffo, PharmD, Clinical Professor, UCSF, Zoe Ngo, PharmD, and Julie Schwenka, PharmD, UCSF
Nausea and vomiting are common side effects of chemotherapy drugs that are used to treat cancer. Some chemotherapy drugs are worse offenders than others In most cases, patients will be given anti-vomiting (antiemetics) and anti-nausea medication
http://www.cancersupportivecare.com/chemotherapy.html
Link added 2006-05-21; reviewed 2008-09-27
RC271.C5.N221.1 - Dealing With ILL Effects of Chemotherapy
Sue Nowlin, RN - Department of Medical Oncology of North Bend Medical Center, Coos Bay, Oregon
Chemotherapy drugs can have a variety of ill effects to the body. Some of these effects (such as vomiting) are short term, while others (such as hair loss) are long term. Some effects (such as nerve damage) can be permanent.
http://www.cancerlynx.com/chemotherapy.html
Link added 2006-01-24; reviewed 2008-09-27
RC271.C5.R68.1 - Antioxidants and Chemoradiotherapy
Ernest H. Rosenbaum, MD
Clinical evidence suggests that the antioxidants may reduce the effectiveness of chemotherapy a few percentage points, which could relate to a large number of potential deaths because of the reduction in therapeutic activity.
http://www.cancersupportivecare.com/antioxidant.html
Link added 2008-09-27;
RC271.C5.R68.2 - Cancer Treatment Side Effects and Solutions
Ernest H. Rosenbaum, MD
Cancer patients who have received radiation or cardiopulmonary toxic chemotherapy drugs merit long-term follow up. Includes information about Chemotherapy-related Cardiac Toxicity, Radiation Therapy-related Cardiac and Pulmonary Toxicity, Renal (Kidney) Toxicity Side Effects Prevention of Cardiopulmonary Side Effects and The Need for Long-term Surveillance
http://www.cancersupportivecare.com/Survivor/comorbid.html
Link added 2007-12-30; reviewed 2008-08-02
RC271.C5.R68.3 - Antioxidants and Chemoradiotherapy
Ernest H. Rosenbaum, MD
Clinical evidence suggests that the antioxidants may reduce the effectiveness of chemotherapy a few percentage points, which could relate to a large number of potential deaths because of the reduction in therapeutic activity.
http://www.cancerlynx.com/antioxidant.html
Link added 2008-10-29;
RC271.C5.R425.1 - Does Adjuvant Chemotherapy for Breast Cancer Cause Cognitive Dysfunction?
Hope S. Rugo, MD
Importance of Understanding Cognitive Deficits Due to Cancer Therapy. A challenge facing cancer survivors as identified by the National Coalition for Cancer Survivorship
http://www.cancersupportivecare.com/chemobrain.pdf
Link added 2006-05-21; reviewed 2008-10-29
RC271.C5.R425.2 - Does Adjuvant Chemotherapy for Breast Cancer Cause Cognitive Dysfunction?
Hope S. Rugo, MD
Importance of Understanding Cognitive Deficits Due to Cancer Therapy. A challenge facing cancer survivors as identified by the National Coalition for Cancer Survivorship
http://www.cancersupportivecare.com/chemobrain.html
Link added 2005-11-06; reviewed 2008-03-04
RC271.C5.S196.1 - Eye Toxicity Issues with Cancer Therapy
Sabrina Selim, MD, Ernest H. Rosenbaum MD, Robert J. Ignoffo, PharmD, FASH, Jean Chan, BA, MA, SEd, Lee Schwartz, MD
A common effect is inflammation of the mucous membranes (mucositis) in the mouth, GI tract and conjunctiva in the eye. Although it is unrealistic to avoid chemotherapy on account of relatively minor eye effects - Includes a graphic of an eye
http://www.cancersupportivecare.com/eye.html
Link added 2006-05-21; reviewed 2008-09-27


RC271.C5.W2.1 - After Hours Care
Agnes Wong, RN, BSN, OCN
Receiving chemotherapy or radiation therapy for the first time can be overwhelming. Your oncology team will try to provide useful information to alleviate your fears and anxiety and to help you in caring for yourself at home. No matter how much your doctor or nurse prepares you, managing side effects from your cancer treatments can be nerve-wracking, especially when the oncology clinic is closed.
http://www.cancerlynx.com/afterhours.html
Link added 2006-06-17; reviewed 2008-09-27

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Link added May 21, 2006 updated November 8, 2009